Abstract
Background: We present the case of a 55-year-old woman, admitted to the Infectious Disease Department of Policlinico Umberto I, Rome, in mid-March 2020, with suspicion of COVID-19 infection.
Objective: The rRT-PCR was negative, and the following CT scan, performed to exclude false-negative results and help diagnosis, was inconclusive. Methods: It was decided to submit the patient to a 99mTc-HMPAO-labelled leukocyte scan. Results: This exam led to the diagnosis of infective endocarditis. Conclusion: In the present pandemic scenario, 99mTc-HMPAO-labelled leukocyte scan represents a reliable imaging technique for differential diagnosis with COVID-19 in patients with confusing clinical signs, possible false-negative rRT-PCR results, and inconclusive CT scan.Keywords: COVID-19, SARS-CoV-2, 99mTc-HMPAO-labelled leukocyte, differential diagnosis, FUO, CT scan.
Graphical Abstract
[http://dx.doi.org/10.1002/jcp.29785] [PMID: 32394467]
[http://dx.doi.org/10.1186/s40779-020-0233-6] [PMID: 32029004]
[http://dx.doi.org/http://dx.doi.org/10.1515/dx-2020-0015]
[http://dx.doi.org/10.3390/jcm9030623] [PMID: 32110875]
[http://dx.doi.org/10.1515/cclm-2020-0285] [PMID: 32172228]
[http://dx.doi.org/10.3348/kjr.2020.0146] [PMID: 32174053]
[http://dx.doi.org/10.1016/j.acra.2020.02.003] [PMID: 32113880]
[http://dx.doi.org/10.1148/radiol.2020200370]
[http://dx.doi.org/10.1148/radiol.2020200432] [PMID: 32073353]
[http://dx.doi.org/10.1016/j.acra.2020.03.003] [PMID: 32204987]
[http://dx.doi.org/10.1016/S1473-3099(16)30141-4] [PMID: 27746163]
[http://dx.doi.org/10.2967/jnumed.114.141895] [PMID: 25453046]