Search Result "inhA mutation"


Progress on the Discovery of Inhibitors of InhA, the FAS II Enoyl-ACP Reductase TB Drug Discovery Targeted on InhA

Journal: Letters in Drug Design & Discovery
Volume: 13 Issue: 6 Year: 2016 Page: 539-546
Author(s): Yi Zhang,Longxiang Xie,Jianping Xie

Development of Modern InhA Inhibitors to Combat Drug Resistant Strains of Mycobacterium tuberculosis

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 5 Year: 2007 Page: 489-498
Author(s): Peter J. Tonge, Caroline Kisker, Richard A. Slayden

Review Article

Structural Basis for Inhibition of Enoyl-[Acyl Carrier Protein] Reductase (InhA) from Mycobacterium tuberculosis

Journal: Current Medicinal Chemistry
Volume: 27 Issue: 5 Year: 2020 Page: 745-759
Author(s): Maurício Boff de Ávila,Gabriela Bitencourt-Ferreira,Walter Filgueira de Azevedo

Targeting InhA, the FASII Enoyl-ACP Reductase: SAR Studies on Novel Inhibitor Scaffolds

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 7 Year: 2012 Page: 672-693
Author(s): Pan Pan,Peter J. Tonge

Research Article

Emergence of Heteroresistance Mycobacterium Tuberculosis in Saudi Arabia

Journal: Infectious Disorders - Drug Targets
Volume: 20 Issue: 4 Year: 2020 Page: 491-494
Author(s): Eltayib H. Ahmed Abakur,Tarig M.S. Alnour,Faisel Abuduhier,Fahad M.A. Albalawi,Khalid A.S. Alfifi

Mini-Review Article

Recent Discoveries of Nitrogen-Containing Heterocyclic Compounds asInhA Inhibitors against Mycobacterium tuberculosis: An Overview

Journal: Infectious Disorders - Drug Targets
Volume: 22 Issue: 8 Year: 2022 Page: 19-29
Author(s): Pratibha D. Gupta,Kalpana N. Tilekar,Neha M. Upadhyay

Enoyl Reductases as Targets for the Development of Anti-Tubercular and Anti-Malarial Agents

Journal: Current Drug Targets
Volume: 8 Issue: 3 Year: 2007 Page: 399-411
Author(s): J. S. Oliveira, I. B. Vasconcelos, I. S. Moreira, D. S. Santos, L. A. Basso

The Mode of Inhibition of Mycobacterium tuberculosis Wild-Type and Isoniazid-Resistant 2-Trans-Enoyl-ACP(CoA) Reductase Enzymes by An Inorganic Complex

Journal: Anti-Infective Agents in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2008 Page: 50-62
Author(s): D. S. Santos, I. B. Vasconcelos, E. Meyer, F. A.M. Sales, I. S. Moreira, L. A. Basso

Research Article

Tryptanthrin Analogues as Inhibitors of Enoyl-acyl Carrier Protein Reductase: Activity against Mycobacterium tuberculosis, Toxicity, Modeling of Enzyme Binding

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 8 Year: 2019 Page: 609-619
Author(s): Gheorghe Duca,Serghei Pogrebnoi,Veaceslav Boldescu,Fatma Aksakal,Andrei Uncu,Vladimir Valica,Livia Uncu,Simona Negres,Florica Nicolescu,Fliur Macaev

New Approaches to Target the Mycolic Acid Biosynthesis Pathway for the Development of Tuberculosis Therapeutics

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 2 Year: 2014 Page: 4357-4378
Author(s): E. Jeffrey North, Mary Jackson, Richard E. Lee

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