Chinese Herbal Formulas and Renal Fibrosis: An Overview

Title:Chinese Herbal Formulas and Renal Fibrosis: An Overview

Volume: 24 Issue: 24

Author(s): Yu-Li Shen, Su-Juan Wang, Khalid Rahman, Li-Jun Zhang*Hong Zhang*

Affiliation:

• Central Laboratory, Seventh People's Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062,China

• Central Laboratory, Seventh People's Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062,China

Keywords: Chinese herbal formula, Bian-Zheng-Lun-Zhi, renal fibrosis, chronic kidney disease, extracellular matrix (ECM), traditional Chinese Medicine (TCM).

Abstract: All forms of chronic kidney disease (CKD) eventually lead to renal fibrosis irrespective of its origin. It is generally characterized by an excessive accumulation and deposition of extracellular matrix (ECM) and to date, no ideal treatment has been established. Bian-Zheng-Lun-Zhi (syndrome differentiation and treatment), a classic feature of traditional Chinese Medicine (TCM), is a unique method used to diagnose and treat the pathology of a disease. Zheng (syndrome) is used to demonstrate the nature of a disease completely in an extensive and specific manner. Chinese herbal formulas are determined according to TCM theory and this review highlights these formulas and suggests a possible mechanism for their use in the treatment of renal fibrosis.

Cite this article as:

Shen Yu-Li , Wang Su-Juan, Rahman Khalid , Zhang Li-Jun *, Zhang Hong*, Chinese Herbal Formulas and Renal Fibrosis: An Overview, Current Pharmaceutical Design 2018; 24 (24) . https://dx.doi.org/10.2174/1381612824666180829103355