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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Tetracyclic Triterpenoids in Herbal Medicines and their Activities in Diabetes and its Complications

Author(s): Kaiser Hamid, Ali Alqahtani, Moon-Sun Kim, Jun-Lae Cho, Pei H. Cui, Chun Guang Li, Paul W. Groundwater and George Q. Li

Volume 15, Issue 23, 2015

Page: [2406 - 2430] Pages: 25

DOI: 10.2174/1568026615666150619141940

Price: $65

Abstract

Tetracyclic triterpenoids, including the dammarane, cucurbitane, cycloartane, lanostane and protostane groups, is a class of triterpenoids widely distributed in various medicinal plants, particularly those commonly used for the treatment of diabetes and its complications, such as Panax ginseng, Panax quinquefolium, Panax notoginseng, Gynostemma pentaphyllum, Astragalus membranaceus, Momordica charantia, and Ganoderma lucidum. This review highlights recent findings on the chemistry and bioactivities of tetracyclic triterpenoids from these plants and other popular herbal medicines.

Keywords: Astragalus, diabetes, Diabetic complications, Ginseng, Gynostemma, Herbal medicines, Tetracyclic triterpenoids.

Graphical Abstract


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