Abstract
Background: New anticancer drug discovery, development and manufacture entered the bottleneck stage. Many limitations of both technology and animal models slow down the anticancer drug developments
Objective: To ease economic burdens for drug developers and general patient populations. Methods: Key factors affecting anticancer drug developments and possible roadmaps for updating drug screening routines worldwide are suggested. Results: Drug development chains must be updated and better drug development paradigms must be established. Conclusions: This world welcomes global participations in anticancer drug developments and utilities.Keywords: Anticancer drug development, neoplasm metastasis, cost-effective, medicinal chemistry, animal models, drug toxicity, cancer stem cells, individualized cancer therapy.
Graphical Abstract
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