Abstract
Glyconanoparticles are the subject of numerous literatures and are emerging for applications in biomedicine, glycoscience, and material science due to their unique properties. They are hybrid materials each of which contains a nanoparticle core surrounded by a carbohydrate shell. The core can be metallic, magnetic, and/or photoluminescent, while the shell may be composed of mono-, di-, oligo- and/or poly-saccharides. Sugars are attached to the surface of the nanoparticles through covalent or non-covalent interaction. Here, we give a brief summary of the synthetic methodologies adopted in the preparation of different types of glyconanoparticles, which can be utilized in various applications including catalysis, drug delivery, vaccine, imaging and study of carbohydrate-lectin interactions.
Keywords: Glyconanoparticles, methodologies, carbohydrate-lectin interactions, biomedicine.
Graphical Abstract
Current Organic Chemistry
Title:Synthesis and Applications of Glyconanoparticles
Volume: 20 Issue: 14
Author(s): Baoyong Liu, Xiaowei Lu, Hong Ruan, Jiwei Cui and Hongguang Li
Affiliation:
Keywords: Glyconanoparticles, methodologies, carbohydrate-lectin interactions, biomedicine.
Abstract: Glyconanoparticles are the subject of numerous literatures and are emerging for applications in biomedicine, glycoscience, and material science due to their unique properties. They are hybrid materials each of which contains a nanoparticle core surrounded by a carbohydrate shell. The core can be metallic, magnetic, and/or photoluminescent, while the shell may be composed of mono-, di-, oligo- and/or poly-saccharides. Sugars are attached to the surface of the nanoparticles through covalent or non-covalent interaction. Here, we give a brief summary of the synthetic methodologies adopted in the preparation of different types of glyconanoparticles, which can be utilized in various applications including catalysis, drug delivery, vaccine, imaging and study of carbohydrate-lectin interactions.
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Cite this article as:
Liu Baoyong, Lu Xiaowei, Ruan Hong, Cui Jiwei and Li Hongguang, Synthesis and Applications of Glyconanoparticles, Current Organic Chemistry 2016; 20 (14) . https://dx.doi.org/10.2174/1385272820666151207194453
DOI https://dx.doi.org/10.2174/1385272820666151207194453 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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