通过蛋白质的丝氨酸/苏氨酸磷酸酶1号和2的眼睛发育规律

Title:Regulation of Eye Development by Protein Serine/Threonine Phosphatases-1 and -2A

Volume: 15 Issue: 10

Author(s): L. Wang, Y. Yang, X. -D. Gong, Z. -X. Huang, Q. Nie, Z. -F. Wang, W. -K. Ji, X. -H. Hu, W. -F. Hu and , L. -L. Gong, L. Zhang, S. Huang, R. -L. Qi, T. -H. Yang, Z. -G. Chen, W. -B. Liu, Y. -Z. Liu and D. W. -C. Li

Affiliation:

关键词: 丝氨酸/苏氨酸磷酸-1和2A号，眼部发育，晶状体变异，发展性细胞凋亡

摘要: The protein serine/threonine phosphatases-1 and -2A are major cellular phosphatases, playing a fundamental role in organisms from prokaryotes to eukaryotes. They contribute to 90% dephosphorylation in eukaryote proteins. In the eye, both phosphatases are highly expressed and display important functions in regulating normal eye development. Moreover, they are implicated in pathogenesis through modulation of stress-induced apoptosis. Here we review the recent progresses on these aspects.

Cite this article as:

L. Wang, Y. Yang, X. -D. Gong, Z. -X. Huang, Q. Nie, Z. -F. Wang, W. -K. Ji, X. -H. Hu, W. -F. Hu and , L. -L. Gong, L. Zhang, S. Huang, R. -L. Qi, T. -H. Yang, Z. -G. Chen, W. -B. Liu, Y. -Z. Liu and D. W. -C. Li , Regulation of Eye Development by Protein Serine/Threonine Phosphatases-1 and -2A, Current Molecular Medicine 2015; 15 (10) . https://dx.doi.org/10.2174/156652401510151125125127