成人唐氏综合征认知功能下降的临床评价

Title:Clinical Assessment of Cognitive Decline in Adults with Down Syndrome

Volume: 13 Issue: 1

Author(s): Marwan Sabbagh and Jamie Edgin

Affiliation:

关键词: Alzheimer’s disease

摘要: Down syndrome is an intellectual disability requiring periodic monitoring of cognition given the near universal presence of Alzheimer’s Disease related neuropathology and high rates of dementia in middle adulthood. We review current approaches to detecting decline in this population, including informant-based measures, dementia screening tools, and neuroimaging techniques. The challenges for detecting decline in this group are discussed, including the need to take into account premorbid cognitive function as well as medical comorbidity.

Cite this article as:

Marwan Sabbagh and Jamie Edgin , Clinical Assessment of Cognitive Decline in Adults with Down Syndrome, Current Alzheimer Research 2016; 13 (1) . https://dx.doi.org/10.2174/1567205012666150921095724