透明质酸药物输送系统的研究进展

Title:Advances in Hyaluronic Acid-Based Drug Delivery Systems

Volume: 17 Issue: 6

Author(s): Yan Jiao, Xin Pang and Guangxi Zhai

Affiliation:

关键词: CD44，化学改性，偶联物，衍生物，透明质酸，纳米载体。

摘要: Hyaluronic acid (HA) is a relatively new polymer for the construction of drug delivery systems. CD44 and the receptor for HA-mediated motility play a key role in vivo for the receptormediated endocytosis of HA. Cellular uptake and the efficiency of tumor-targeted drug delivery are supposed to increase through utilizing HA as drug carriers. Currently, HA has provided a promising platform to physically encapsulate or chemically conjugate with various drugs. In this review, we presented the most latest advances in HA-based drug delivery systems and some forward-looking ideas are discussed.

Cite this article as:

Yan Jiao, Xin Pang and Guangxi Zhai , Advances in Hyaluronic Acid-Based Drug Delivery Systems, Current Drug Targets 2016; 17 (6) . https://dx.doi.org/10.2174/1389450116666150531155200