Progress of In Vivo Electroporation in the Rodent Brain

Title:Progress of In Vivo Electroporation in the Rodent Brain

Volume: 14 Issue: 3

Author(s): Xue-Feng Ding, De-Lin Ma, Qiang Zhang, Wei Peng, Ming Fan and William Z. Suo

Affiliation:

Keywords: Bilateral electroporation, brain disorder, gene therapy, in vivo electroporation, rodent brain.

Abstract: In vivo electroporation is one of the most efficient methods for introducing the nucleic acids into the target tissues, and thus plays a pivotal role in gene therapeutic studies. In vivo electroporation in rodent brains is often involved in injection of nucleic acids into the brain ventricle or specific area and then applying appropriate electrical field to the correct area. Better understanding of the progress of electroporation in rodent brain may further facilitate gene therapeutic studies on some brain disorders. For this purpose, we briefly summarized the advantages, the procedures and recent progress of transferring nucleic acids into the rodent brain using in vivo electroporation.

Cite this article as:

Ding Xue-Feng, Ma De-Lin, Zhang Qiang, Peng Wei, Fan Ming and Suo Z. William, Progress of In Vivo Electroporation in the Rodent Brain, Current Gene Therapy 2014; 14 (3) . https://dx.doi.org/10.2174/1566523214666140424145305