Evolving Therapeutic Targets in Ischemic Stroke: A Concise Review

Title:Evolving Therapeutic Targets in Ischemic Stroke: A Concise Review

Volume: 14 Issue: 4

Author(s): Sinoy Sugunan, Diya Binoy Joseph and G. K. Rajanikant

Affiliation:

Keywords: Ischemic stroke, therapeutic targets, excitotoxicity, NADPH oxidase, inflammation, MHC-I, neuroplasticity

Abstract: Ischemic stroke is the leading cause of mortality and morbidity worldwide for which the assemblage of therapeutic interventions has remained outstandingly limited. Several new insights into the causes of neuronal death during ischemic event have led to the identification of some important novel targets for intervention. This article highlights some of the promising protein targets, which are in the validation process and have the potential to get translated into viable neurotherapeutics against ischemic stroke.

Cite this article as:

Sugunan Sinoy, Binoy Joseph Diya and K. Rajanikant G., Evolving Therapeutic Targets in Ischemic Stroke: A Concise Review, Current Drug Targets 2013; 14 (4) . https://dx.doi.org/10.2174/1389450111314040011