Ventilatory Support in Persistent Pulmonary Hypertension of the Newborn

Title: Ventilatory Support in Persistent Pulmonary Hypertension of the Newborn

Volume: 8 Issue: 1

Author(s): Maria Esther Jurfest Ceccon and Werther Brunow de Carvalho

Affiliation:

Keywords: Mechanical ventilation, hypertension pulmonary persistent neonatal, exogenous surfactant, nitric oxide, phosphodiesterases inhibitors, vasoreactivity, PFC syndrome, high-frequency oscillatory ventilation, coarctation of the aorta, meconium aspiration syndrome

Abstract: Objective: Present a review about the use of mechanical pulmonary ventilation in Hypertension Pulmonary Persistent Neonatal (HPPN), the conventional mode and the indication of high-frequency oscillatory ventilation (HFOV). Also present other approaches, such as therapeutics use of exogenous surfactant, inhaled nitric oxide, phosphodiesterases inhibitors and extracorporeal membrane oxygenation. Data Source: It has been used in articles obtained in the Pub Med, Medline, Cochrane BVS, databases, in which there are topics about mechanical ventilation in Hypertension Pulmonary Persistent Neonatal and others treatments used in the newborn with HPPN. Conclusion: The effective treatments used in HPPN are a conventional, not very aggressive ventilatory strategy; HFOV; inhaled nitric oxide and vasodilators medications that act on the lungs rather than on the whole system, and, in newborns that do not respond to these treatments, the use of extracorporeal membrane oxygenation.

Cite this article as:

Esther Jurfest Ceccon Maria and Brunow de Carvalho Werther, Ventilatory Support in Persistent Pulmonary Hypertension of the Newborn, Current Respiratory Medicine Reviews 2012; 8 (1) . https://dx.doi.org/10.2174/157339812798868834