Proteomic Analysis of Mitochondria in Raji Cells Following Exposure to Radiation: Implications for Radiotherapy Response

Title: Proteomic Analysis of Mitochondria in Raji Cells Following Exposure to Radiation: Implications for Radiotherapy Response

Volume: 16 Issue: 11

Author(s): Yujie Jiang, Xin Liu, Xiaosheng Fang and Xin Wang

Affiliation:

Keywords: Mitochondria, Comparative proteomics, Raji, Radiation, Biomarker

Abstract: Radioresistance represents a major obstacle to a successful outcome for the treatment of non-Hodgkins lymphoma (NHL). Here we performed a global differential proteome analysis of the mitochondria in Raji cells exposed to radiation. The results showed that 23 differentially expressed proteins were identified. Furthermore, GAPDH, RECQL4, MKI67, and ATAD3B could serve as potential biomarkers of radioresistance.

Cite this article as:

Jiang Yujie, Liu Xin, Fang Xiaosheng and Wang Xin, Proteomic Analysis of Mitochondria in Raji Cells Following Exposure to Radiation: Implications for Radiotherapy Response, Protein & Peptide Letters 2009; 16 (11) . https://dx.doi.org/10.2174/092986609789353646