Early Features in Frontotemporal Dementia

Title: Early Features in Frontotemporal Dementia

Volume: 6 Issue: 4

Author(s): Ana Maria Villamizar Caycedo, Bruce Miller, Joel Kramer and Katya Rascovsky

Affiliation:

Abstract: Frontotemporal dementia is a disorder of paralimbic prefrontal-insular circuitry. The disorder is often sporadic but can be caused by genetic mutations in tau, progranulin, valosin, TDP-43 and CHMP2b. The major clinical manifestations of FTD include addictive behaviors, disinhibition, apathy, overeating and loss of sympathy and empathy for others. Treatment is currently focused around symptoms but disease-modifying therapies seem feasible.

Cite this article as:

Villamizar Caycedo Maria Ana, Miller Bruce, Kramer Joel and Rascovsky Katya, Early Features in Frontotemporal Dementia, Current Alzheimer Research 2009; 6 (4) . https://dx.doi.org/10.2174/156720509788929255