Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease

Title: Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease

Volume: 8 Issue: 5

Author(s): S. Bastianetto, S. Krantic and R. Quirion

Affiliation:

Keywords: Alzheimer's disease, polyphenols, neuroprotection

Abstract: Beta-amyloid (Aβ) likely plays a pivotal role in the etiology of Alzheimers disease (AD). Consequently, Aβ-associated pathways are targets for the development of possible effective AD therapies. This review first updates strategies aimed at the inhibition of Aβ formation and then discusses the role of food-derived polyphenols as putative antiamyloid drugs.

Cite this article as:

Bastianetto S., Krantic S. and Quirion R., Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease, Mini-Reviews in Medicinal Chemistry 2008; 8 (5) . https://dx.doi.org/10.2174/138955708784223512