Apoptotic Signaling Pathways as a Target for the Treatment of Liver Diseases

Title: Apoptotic Signaling Pathways as a Target for the Treatment of Liver Diseases

Volume: 8 Issue: 14

Author(s): J. L. Mauriz, M. J. Tunon and J. Gonzalez-Gallego

Affiliation:

Keywords: Liver, hepatitis, alcohol, hepatocarcinoma, cholestasis, fulminant hepatic failure, steatohepatitis, fibrosis

Abstract: Dysregulation of apoptosis is a major contributor to the initiation and aggravation of liver injury. Agents that modulate apoptosis may be of therapeutic benefit in a number of liver diseases, and research related to cell type-specific activation or inhibition of apoptotic signaling pathways will provide new strategies for treatment.

Cite this article as:

Mauriz L. J., Tunon J. M. and Gonzalez-Gallego J., Apoptotic Signaling Pathways as a Target for the Treatment of Liver Diseases, Mini-Reviews in Medicinal Chemistry 2008; 8 (14) . https://dx.doi.org/10.2174/138955708786786499