Application of Olefin Cross-Metathesis to the Synthesis of Biologically Active Natural Products

Title: Application of Olefin Cross-Metathesis to the Synthesis of Biologically Active Natural Products

Volume: 5 Issue: 15

Author(s): Joelle Prunet

Affiliation:

Keywords: furaquinocin B, platelet aggregation, reductive cyclization, Deprotection, homodimerization, Amphidinium sp, pyridinium para-toluenesulfonate (PPTS)

Abstract: An overview of the use of olefin cross-metathesis in the synthesis of biologically active natural products is presented. The diverse examples are organized according to the outcome of the olefin constructed by the cross-metathesis reaction: this olefin can be either present in the final product, reduced, engaged in other transformations, or involved in tandem processes.

Cite this article as:

Prunet Joelle, Application of Olefin Cross-Metathesis to the Synthesis of Biologically Active Natural Products, Current Topics in Medicinal Chemistry 2005; 5 (15) . https://dx.doi.org/10.2174/156802605775009801