Raxofelast, (±)5-(Acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic Acid: A New Antioxidant to Modulate the Inflammatory Response During Ischemia-Reperfusion Injury and Impaired Wound Healing

Title: Raxofelast, (±)5-(Acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic Acid: A New Antioxidant to Modulate the Inflammatory Response During Ischemia-Reperfusion Injury and Impaired Wound Healing

Volume: 7 Issue: 3

Author(s): A. Bitto, L. Minutoli, F. Squadrito, F. Polito and D. Altavilla

Affiliation:

Keywords: Raxofelast, inflammation, ischemia/reperfusion injury, wound healing, diabetes, safety

Abstract: Raxofelast, also named IRFI 016 or (±)5-(Acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic acid, belongs to a family of novel molecules designed with the aim to maximize antioxidant potency of phenols related to Vitamin E ( α-tocopherol). This review will focus on the antioxidant and radical scavenging activity of this new promising compound.

Cite this article as:

Bitto A., Minutoli L., Squadrito F., Polito F. and Altavilla D., Raxofelast, (±)5-(Acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic Acid: A New Antioxidant to Modulate the Inflammatory Response During Ischemia-Reperfusion Injury and Impaired Wound Healing, Mini-Reviews in Medicinal Chemistry 2007; 7 (3) . https://dx.doi.org/10.2174/138955707780059835