Chromenopyridines: Promising Scaffolds for Medicinal and Biological Chemistry

Title: Chromenopyridines: Promising Scaffolds for Medicinal and Biological Chemistry

Volume: 18 Issue: 31

Author(s): L. J. Nunez-Vergara, J. A. Squella, P. A. Navarrete-Encina, E. Vicente-Garcia, S. Preciado and R. Lavilla

Affiliation:

Keywords: Azines, benzopyran, chromene, coumarin, drug-like scaffolds, heterocycles, multicomponent reactions, privileged structures, pyridine, synthetic methods

Abstract: Chromenopyridines constitute a structurally diverse class of compounds with a wide range of bioactivities and increasing presence in drugs. Here we analyze the scope of the synthetic methodology to access this nucleus with emphasis on multicomponent reactions and robust methodologies. Reactivity issues, medicinal applications and other properties are also reviewed.

Cite this article as:

J. Nunez-Vergara L., A. Squella J., A. Navarrete-Encina P., Vicente-Garcia E., Preciado S. and Lavilla R., Chromenopyridines: Promising Scaffolds for Medicinal and Biological Chemistry, Current Medicinal Chemistry 2011; 18 (31) . https://dx.doi.org/10.2174/092986711797535272