Abstract
Microarrays provide the biological research community with tremendously rich, sensitive and detailed information on gene expression profiles. Gene expression profiling and gene expression patterns have been found useful for solving a wide variety of important biological and biomedical problems, including the study of metabolic pathways, inference of the functions of unknown genes, diagnosis of diseased states, as well as facilitating the development of individualized drug treatments through pharmacogenomics. Given the significant impact of microarray gene expression data in biological and biomedical research, this breakthrough technology urgently needs the assistance of advanced computational methods for interpreting and utilizing the raw information. This paper reviews several main research directions and methods in the analysis of microarray gene expression data.
Keywords: Microarrays, gene expression, data analysis, image processing, signal processing, pattern classification, machine learning, computational techniques
Current Bioinformatics
Title: Analysis of Microarray Gene Expression Data
Volume: 1 Issue: 1
Author(s): Tuan D. Pham, Christine Wells and Denis I. Crane
Affiliation:
Keywords: Microarrays, gene expression, data analysis, image processing, signal processing, pattern classification, machine learning, computational techniques
Abstract: Microarrays provide the biological research community with tremendously rich, sensitive and detailed information on gene expression profiles. Gene expression profiling and gene expression patterns have been found useful for solving a wide variety of important biological and biomedical problems, including the study of metabolic pathways, inference of the functions of unknown genes, diagnosis of diseased states, as well as facilitating the development of individualized drug treatments through pharmacogenomics. Given the significant impact of microarray gene expression data in biological and biomedical research, this breakthrough technology urgently needs the assistance of advanced computational methods for interpreting and utilizing the raw information. This paper reviews several main research directions and methods in the analysis of microarray gene expression data.
Export Options
About this article
Cite this article as:
Pham D. Tuan, Wells Christine and Crane I. Denis, Analysis of Microarray Gene Expression Data, Current Bioinformatics 2006; 1 (1) . https://dx.doi.org/10.2174/157489306775330642
DOI https://dx.doi.org/10.2174/157489306775330642 |
Print ISSN 1574-8936 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-392X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
One-Compound-Multi-Target: Combination Prospect of Natural Compounds with Thrombolytic Therapy in Acute Ischemic Stroke
Current Neuropharmacology Dynamic Contrast Enhanced Magnetic Resonance Imaging in Oncology:Theory, Data Acquisition,Analysis, and Examples
Current Medical Imaging A New Approach for Cancer Immunotherapy Based on the Cancer Stem Cell Antigens Properties
Current Molecular Medicine Imaging Primary Brain Tumors by Single-Photon Emission Computerized Tomography (SPECT) with Technetium-99m Sestamibi (MIBI) and Tetrofosmin
Current Medical Imaging Circumventing Melanoma Chemoresistance by Targeting DNA Repair
Current Medicinal Chemistry Colloidal Polymeric Nanoparticles and Brain Drug Delivery
Current Drug Delivery Neuroprotective Effects of Citrus Fruit-Derived Flavonoids, Nobiletin and Tangeretin in Alzheimer's and Parkinson's Disease
CNS & Neurological Disorders - Drug Targets Role of Tyrosine Phosphatase Inhibitors in Cancer Treatment with Emphasis on SH2 Domain-Containing Tyrosine Phosphatases (SHPs)
Anti-Cancer Agents in Medicinal Chemistry Nongenomic Actions of Thyroid Hormones: From Basic Research to Clinical Applications. An Update
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) The Interaction Between FAK, MYCN, p53 and Mdm2 in Neuroblastoma
Anti-Cancer Agents in Medicinal Chemistry Recent Patents on Heat Shock Proteins Targeting Antibodies
Recent Patents on Anti-Cancer Drug Discovery Review of Clinic Trials: Agents Targeting c-Met
Reviews on Recent Clinical Trials Patent Selections
Recent Patents on Inflammation & Allergy Drug Discovery The Use of the Inhibitory Receptors for Modulating the Immune Responses
Current Pharmaceutical Design B7-H3 Immune Checkpoint Protein in Human Cancer
Current Medicinal Chemistry Genetic Modification of Natural Killer Cells for Leukemia Therapies
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Neonatal Germ Cell Tumors
Current Pediatric Reviews Nucleic-Acid Delivery Using Lipid Nanocapsules
Current Pharmaceutical Biotechnology Detection and Specific Targeting of Hypoxic Regions within Solid Tumors: Current Preclinical and Clinical Strategies
Current Medicinal Chemistry The Immune System in Cancer Prevention, Development and Therapy
Anti-Cancer Agents in Medicinal Chemistry