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Current Nanoscience

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ISSN (Print): 1573-4137
ISSN (Online): 1875-6786

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Research Article

Enzymatic Activity of Glucose Oxidase on Mesoporous TiO2:Mn Surfaces

Author(s): Leda G. Bousiakou*, Peter J. Dobson and Omar M. Aldossary

Volume 20, Issue 2, 2024

Published on: 12 May, 2023

Page: [272 - 278] Pages: 7

DOI: 10.2174/1573413719666230403103754

open access plus

Abstract

Introduction: It is well known, that titanium dioxide (TiO2) nanoparticles can lead to the generation of reactive oxygen species (ROS) upon photoexcitation.

Methods: In this work, we investigated mesoporous surfaces based on TiO2 nanoparticles doped with 0.6-0.7% manganese (Mn), which showed reduced photoactivity and were based on the more stable rutile polymorph of titania.

Results: In particular, we showed spectrophotometrically that the enzyme glucose oxidase (GOD) can be successfully adsorbed up to 80% while retaining its bioactivity in contact with the TiO2:Mn-based surface.

Conclusion: We propose that this study could potentially give rise to biocompatible surfaces for biosensing applications.

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