Divergences in homeodomains of hox genes and von baer's law

Title:Divergences in homeodomains of hox genes and von baer's law

Volume: 7 Issue: 2

Author(s): Rong-Qiao He*Jun-Lan Yao

Affiliation:

• Lab of Visual Information Processing, Institute of Biophysics, The Chinese Academy of Sciences, Beijing I 00 IO I, China

Abstract: Divergences among homeodomains coded by Hox clusters of human beings have been analyzed with both methods of dynamic programming [I] and hydropathic mass [2). Homeodomains of the anterior genes (Hox A-1 to -4), including the paralogs of Hox B and Hox D, showed more distinguishable divergences than those of the posterior genes (from Hox A-5 to -13). The homeodomains grew exponentially more divergent in progression from the paralogue group I to 13 along a Hox complex. The divergence of homeodomains of Hox B-1 between C. elegans and human was small, but it became larger between those of the posterior genes. It appears that Hox genes should be involved in Von Baer's law.

Cite this article as:

He Rong-Qiao*, Yao Jun-Lan, Divergences in homeodomains of hox genes and von baer's law, Protein & Peptide Letters 2000; 7 (2) . https://dx.doi.org/10.2174/092986650702221206115639