摘要
有越来越多的文献表明姜黄素的积极治疗潜力.姜黄素或二茂酰甲烷是从植物姜黄中获得的多酚。姜黄素广泛用于阿育吠陀和中医的各种病症。姜黄素在甲状腺疾病中的作用已经通过其对各种生物途径的作用得到证明,包括抗炎,抗氧化,抗增殖,细胞凋亡,血管生成,细胞周期和转移。在本文中,我们回顾了最近关于姜黄素在甲状腺功能障碍中的应用的文献,包括甲状腺功能亢进和甲状腺功能减退,并讨论了这些效应的分子机制。本综述旨在总结姜黄素对甲状腺治疗效果的丰富研究。
关键词: 姜黄素,甲状腺,分子机制,激素,促甲状腺激素,垂体。
Current Medicinal Chemistry
Title:Cellular and Molecular Mechanisms of Curcumin in Thyroid Gland Disorders
Volume: 29 Issue: 16
关键词: 姜黄素,甲状腺,分子机制,激素,促甲状腺激素,垂体。
摘要: There is growing literature on the positive therapeutic potentials of curcumin. Curcumin or diferuloylmethane is a polyphenol obtained from the plant Curcuma longa. Curcumin is widely used in Ayurvedic and Chinese medicine for various conditions. The role of curcumin in thyroid gland disorders has been demonstrated by its effects on various biological pathways, including anti-inflammatory, antioxidant, anti-proliferative, apoptosis, angiogenesis, cell cycle and metastasis. In this paper, we have reviewed the recent literature on curcumin applications for thyroid dysfunction, including hyperthyroidism and hypothyroidism, and discussed the molecular mechanisms of these effects. This review aims to summarize the wealth of research related to the therapeutic effect of curcumin on the thyroid gland.
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Cite this article as:
Cellular and Molecular Mechanisms of Curcumin in Thyroid Gland Disorders, Current Medicinal Chemistry 2022; 29 (16) . https://dx.doi.org/10.2174/0929867329666220210145033
DOI https://dx.doi.org/10.2174/0929867329666220210145033 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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