A Comprehensive Review on Recently Detected Herbal Phytoactives Having Anti-Diabetic Potential for Various Diabetes-Related Complications

Title:A Comprehensive Review on Recently Detected Herbal Phytoactives Having Anti-Diabetic Potential for Various Diabetes-Related Complications

Volume: 7 Issue: 5

Author(s): Pranay Wal*, Ankita Wal, Rashmi Saxena Pal and Priya Singh

Affiliation:

• Institute of Pharmacy , PSIT, Kanpur, 209305,India

Keywords: Diabetes, insulin, herbal, phytoactives, potential, natural compounds.

Abstract:

Background: Diabetes is a metabolic, endocrine disorder that is featured by hyperglycemia and glucose intolerance, primarily due to beta cell destruction, with insulin resistance playing a secondary role. It is treated with the help of many chemical-based drugs as well as natural derivatives.

Objective: There is an urgent need to develop new efficacious, cheaper and more available drugs to face this growing public health challenge. Many anti-diabetic drugs are often associated with many adverse effects.

Materials & Methods: Literature was reviewed in a narrative manner in order to obtain information regarding active phytoactives present in different plants. Anti-diabetic drugs are often loaded with side effects; therefore, this review was carried out for the selection of effective natural therapeutic moieties with less or no adverse effects.

Results: In this review article, we have described the details of recently detected bioactive compounds present in different natural substances which can be used effectively for diabetes-related adversities.

Conclusion: Natural products-based bioactive molecules have been proven to improve insulin resistance and other related complications through suppression of inflammatory signaling pathways.

Cite this article as:

Wal Pranay *, Wal Ankita , Pal Saxena Rashmi and Singh Priya, A Comprehensive Review on Recently Detected Herbal Phytoactives Having Anti-Diabetic Potential for Various Diabetes-Related Complications, Current Traditional Medicine 2021; 7 (5) : e130121190300 . https://dx.doi.org/10.2174/2215083807666210114114334