未折叠蛋白质反应的细胞间传递-这是一个真正的现象吗？

Title:Cell-to-Cell Transmission of the Unfolded Protein Response - Is it a Real Phenomenon?

Volume: 28 Issue: 22

关键词: 内质网、未折叠蛋白反应、条件培养基、UPR、未折叠蛋白、细胞间细胞传递、反应。

摘要: Cell-to-cell transmission of the unfolded protein response (UPR) is one of the most exciting observations recently made in cell biology. One of the most efficient tools to induce UPR response in cell culture is treatment with specific compounds leading to accumulation of misfolded proteins in endoplasmic reticulum. In this article we discussed opposite opinions regarding application of this approach and possible sources of experimental artefacts.

Cite this article as:

Cell-to-Cell Transmission of the Unfolded Protein Response - Is it a Real Phenomenon?, Current Medicinal Chemistry 2021; 28 (22) . https://dx.doi.org/10.2174/0929867327999201105163402