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Current Cardiology Reviews

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ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

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Review Article

Syndrome of Supine Hypertension with Orthostatic Hypotension: Pathophysiology and Clinical Approach

Author(s): Aamir Ahmed, Mohammed Ruzieh*, Shaffi Kanjwal and Khalil Kanjwal

Volume 16, Issue 1, 2020

Page: [48 - 54] Pages: 7

DOI: 10.2174/1573403X15666190617095032

Price: $65

Abstract

This article is intended to provide guidance and clinical considerations for physicians managing patients suffering from supine hypertension with orthostatic hypotension, referred to as “SH-OH”. We review the normal physiologic response to orthostasis, focusing on the appropriate changes to autonomic output in this state. Autonomic failure is discussed with a generalized overview of the disease and examination of specific syndromes that help shed light on the pathophysiology of SH-OH. The goal of this review is to provide a better framework for clinical evaluation of these patients, review treatment options, and ultimately work toward achieving a better quality of life for patients afflicted with this disease.

Keywords: Orthostatic hypotension, supine hypertension, autonomic failure, dysautonomia, blood pressure, orthostatic posture.

Graphical Abstract

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