Sensing, Transport and Other Potential Biomedical Applications of Pseudopeptides

Enrico        Faggi; Santiago    V.   Luis; Ignacio       Alfonso
doi:10.2174/0929867325666180301091040
Abstract

Pseudopeptides are privileged synthetic molecules built from the designed combination of peptide-like and abiotic artificial moieties. Consequently, they are benefited from the advantages of both families of chemical structures: modular synthesis, chemical and functional diversity, tailored three-dimensional structure, usually high stability in biological media and low non-specific toxicity. Accordingly, in the last years, these compounds have been used for different biomedical applications, ranging from bio-sensing, ion transport, the molecular recognition of biologically relevant species, drug delivery or gene transfection. This review highlights a selection of the most remarkable and recent advances in this field.
Keywords: Pseudopeptides, sensing, transport, cation coordination, anion coordination, gene delivery.
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DOI https://dx.doi.org/10.2174/0929867325666180301091040	Print ISSN 0929-8673
Publisher Name Bentham Science Publisher	Online ISSN 1875-533X
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