摘要
背景：阿尔茨海默病（AD）是最常见和研究良好的神经变性疾病（ND）。 AD的生物学途径，病理生理学和遗传学显示与其他ND的共同点，帕金森氏病（PD），肌萎缩性侧索硬化（ALS），亨廷顿舞蹈病（HD），朊病毒病和牙髓 - 苍白球囊性萎缩症（DRPLA）。许多ND共享共同特征和分子机制表明，病理学可能是直接可比的，并且涉及疾病预防和发展高效疗法。 方法：在本综述中，对AD的病理生理学，临床症状和可用治疗情况进行了简要的介绍，特别强调AD。这些致命的ND中的共同点为治疗进展提供了支持，并增强了对疾病表现的理解。 结论：研究集中在生物学途径，细胞机制和遗传学上的共同之处，可能为研究人员提供了多种新型共同靶点，用于预防和发展多种神经退行性疾病的有效常用药物。
关键词: 神经变性疾病，阿尔茨海默病，帕金森病，亨廷顿病，肌萎缩性侧索硬化，生物学途径。
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