Montmorillonite K-10 Clay Mediated Green Synthesis of 2-Amino-4-aryl thiazole Derivatives from α-Brominated Aralkyl Ketones in Water

Title:Montmorillonite K-10 Clay Mediated Green Synthesis of 2-Amino-4-aryl thiazole Derivatives from α-Brominated Aralkyl Ketones in Water

Volume: 2 Issue: 2

Author(s): Pinjari Md. K. Mohinuddin, Reddy B. Mohan, Sangita D. Kumar and Nallagondu C.G. Reddy

Affiliation:

Keywords: Montmorillonite K-10 clay, phenacyl bromides, thiourea, water, 2-amino-4-aryl thiazoles.

Abstract: Montmorillonite K-10 clay has been identified as an efficient and green catalyst for the synthesis of 2-amino-4-aryl thiazole derivatives (3) in good to excellent isolated yields (80-96%) from α-brominated aralkyl ketones (1) and thiourea (2) in aqueous medium at 25-30°C. The present procedure offers advantages of short reaction time, simple work-up, high yields of products and the catalyst is environmentally benign and exhibits remarkable reusable activity by four times.

Cite this article as:

Mohinuddin Md. K. Pinjari, Mohan B. Reddy, Kumar D. Sangita and Reddy C.G. Nallagondu, Montmorillonite K-10 Clay Mediated Green Synthesis of 2-Amino-4-aryl thiazole Derivatives from α-Brominated Aralkyl Ketones in Water, Current Green Chemistry 2015; 2 (2) . https://dx.doi.org/10.2174/2213346102666150205100538

DOI https://dx.doi.org/10.2174/2213346102666150205100538	Print ISSN 2213-3461
Publisher Name Bentham Science Publisher	Online ISSN 2213-347X