Development of Safe and Economical Synthesis of Isoxazole

Title:Development of Safe and Economical Synthesis of Isoxazole

Volume: 10 Issue: 9

Author(s): Lakshmikant H. Nitlikar and Devanand B. Shinde

Affiliation:

Keywords: Isoxazole, Malonaldehyde tetraethyl acetal, di (1, 3-dioxolan-2-yl) methane.

Abstract: Isoxazole is a five membered heterocyclic compound having various pharmacological actions. The new practical synthesis of isoxazole from the easily available malonadehyde tetraethyl acetal by avoiding the use of toxic reagent such as cadmium chloride under environment friendly conditions has been developed.

Cite this article as:

Nitlikar H. Lakshmikant and Shinde B. Devanand, Development of Safe and Economical Synthesis of Isoxazole, Letters in Organic Chemistry 2013; 10 (9) . https://dx.doi.org/10.2174/15701786113109990032