A Review of Natural and Modified Betulinic, Ursolic and Echinocystic Acid Derivatives as Potential Antitumor and Anti-HIV Agents

Title: A Review of Natural and Modified Betulinic, Ursolic and Echinocystic Acid Derivatives as Potential Antitumor and Anti-HIV Agents

Volume: 3 Issue: 6

Author(s): I. Baglin, A.- C. Mitaine-Offer, M. Nour, K. Tan, C. Cave and M.- A. Lacaille-Dubois

Affiliation:

Keywords: betulinic, ursolic, echinocystic acid, antitumor, anti-hiv agents, anti-hiv activities

Abstract: The aim of this review is to update current knownledge on the betulinic, ursolic and echinocystic acids and their natural and semisynthetic analogs, focussing on their cytotoxic and anti-HIV activities. Then, the last results of the authors team on unusual semisynthetic derivatives of these triterpenoids will be presented in order to establish structure / activity relationships.

Cite this article as:

Baglin I., Mitaine-Offer C. A.-, Nour M., Tan K., Cave C. and Lacaille-Dubois A. M.-, A Review of Natural and Modified Betulinic, Ursolic and Echinocystic Acid Derivatives as Potential Antitumor and Anti-HIV Agents, Mini-Reviews in Medicinal Chemistry 2003; 3 (6) . https://dx.doi.org/10.2174/1389557033487917