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Current Cardiology Reviews

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ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

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Review Article

Physiological Evidence and Therapeutic Outcomes of Vitamin D on Cardiovascular Diseases

Author(s): Abolfazl Zendehdel, Amir Shakarami and Ehsan Sekhavati Moghadam*

Volume 20, Issue 1, 2024

Published on: 18 January, 2024

Article ID: e180124225801 Pages: 10

DOI: 10.2174/011573403X263417231107110618

Price: $65

Abstract

Vitamin D hormone is an important regulator of various physiological functions, and its deficiency is characterized by an imbalance in parathyroid hormone and calcium homeostasis. The role of vitamin D in cardiovascular physiology is well demonstrated in animal and humanbased studies. In this context, hyperlipidemia, increased atherogenic plaques, cardiac inflammation, hypertension, myocarditis, myocardial infarction, and heart failure are some of the commonest known conditions connected with vitamin D deficiency. Supplementation of vitamin D is recommended to achieve normal serum vitamin D concentrations, nonetheless, in clinical trials often seen discrepancies concerning the supplementation effects and effectiveness. This review summarizes the data on the role of vitamin D in cardiovascular health along with some recent clinical findings regarding the effects of vitamin D supplementation.

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