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Current Medical Imaging

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ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

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Case Report

A Case Report of Primary Extranodal Diffuse Large B-Cell Lymphoma Involving the Masseter Muscle: Histological-Radiological Correlation

Author(s): Sunggong Lim, Hye Jin Baek* and Young Hoon Kang

Volume 19, Issue 7, 2023

Published on: 07 October, 2022

Article ID: e310822208395 Pages: 7

DOI: 10.2174/1573405618666220831162014

Price: $65

Abstract

Introduction: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non- Hodgkin’s lymphoma (NHL). However, the primary skeletal muscle involvement of DLBCL is extremely rare, comprising less than 1% of all the extranodal lymphoma. To date, only 8 cases of extranodal NHL involving the masticator muscles have been reported in the literature.

Case Presentation: A 70-year-old male presented with a rapid progression of painless facial swelling in the left cheek. CT, MRI and US findings demonstrated a well-defined, soft tissue mass in the left masseter muscle. The histopathological diagnosis was DLBCL by US-guided core needle biopsy. The patient received three cycles of chemotherapy.

Conclusion: Because of its rarity, primary muscular DLBCL must be considered in differential diagnosis with all possible causes of intramuscular masses. Even the integration of multiple imaging methods does not lead to a definitive diagnosis, the biopsy is the only possibility for an early diagnosis. Therefore, clinical awareness and high suspicion of this disease are important for early diagnosis and proper treatment.

Keywords: Case report, Diffuse large B cell lymphoma, Lymphoma, Muscle, CT, MRI, Ultrasonography

Graphical Abstract

[1]
Spetsieris N, Giannakopoulou N, Variami E, et al. Isolated skeletal muscle recurrence of an originally nodal diffuse large B cell lymphoma. Medicine (Baltimore) 2018; 97(3): e9608.
[http://dx.doi.org/10.1097/MD.0000000000009608] [PMID: 29504987]
[2]
Guastafierro S, Falcone U, Petriccione L, et al. An unusual cause of facial swelling: Primary extranodal non-Hodgkin lymphoma of the masseter muscle. Am J Med Sci 2011; 341(2): 160-2.
[http://dx.doi.org/10.1097/MAJ.0b013e3181fb7136] [PMID: 21107233]
[3]
Hwang S. Imaging of lymphoma of the musculoskeletal system. Radiol Clin North Am 2008; 46(2): 379-96. x.
[http://dx.doi.org/10.1016/j.rcl.2008.03.008] [PMID: 18619386]
[4]
Min HJ, Kim KS. Primary Non-Hodgkin’s lymphoma originating from the masseter muscle. Bangladesh J Med Sci 2021; 20(1): 181-6.
[http://dx.doi.org/10.3329/bjms.v20i1.50367]
[5]
Chong J, Som PM, Silvers AR, Dalton JF. Extranodal non-Hodgkin lymphoma involving the muscles of mastication. AJNR Am J Neuroradiol 1998; 19(10): 1849-51.
[PMID: 9874535]
[6]
Kikuchi K, Inoue H, Miyazaki Y, et al. Adult sporadic burkitt lymphoma of the oral cavity: A case report and literature review. J Oral Maxillofac Surg 2012; 70(12): 2936-43.
[http://dx.doi.org/10.1016/j.joms.2012.02.017] [PMID: 22520562]
[7]
Lee VS, Martinez S, Coleman RE. Primary muscle lymphoma: Clinical and imaging findings. Radiology 1997; 203(1): 237-44.
[http://dx.doi.org/10.1148/radiology.203.1.9122401] [PMID: 9122401]
[8]
Hatem J, Bogusz AM. An unusual case of extranodal diffuse large Bcell lymphoma infiltrating skeletal muscle: A case report and review of the literature. Case Reports in Pathology 2016; 2016.
[9]
Glass AG, Karnell LH, Menck HR. The national cancer data base report on non-hodgkin’s lymphoma. Cancer 1997; 80(12): 2311-20.
[http://dx.doi.org/10.1002/(SICI)1097-0142(19971215)80:12<2311:AID-CNCR13>3.0.CO;2-X] [PMID: 9404709]
[10]
Muralee Mohan C, Thakral A, Bhat SK. Primary extranodal non-Hodgkin’s lymphoma involving masseter and buccinator muscles. Int J Oral Maxillofac Surg 2012; 41(11): 1393-6.
[http://dx.doi.org/10.1016/j.ijom.2011.09.025] [PMID: 22464613]
[11]
Set PAK, Somers JM, Britton PD, Freer CEL. Pictorial review: Benign and malignant enlargement of the pterygo-masseteric muscle complex. Clin Radiol 1993; 48(1): 57-60.
[http://dx.doi.org/10.1016/S0009-9260(05)80110-2] [PMID: 8370222]
[12]
Ceysens C, Horvath M, Termote JL, Lemahieu SF. Extranodal non-Hodgkin lymphoma of the head and neck presenting as a mandibular swelling: report of two cases. JBR-BTR 1992; 75(1): 37-9.
[PMID: 1569003]
[13]
Connor SEJ, Chavda SV, West R. Recurrence of non-Hodgkin’s lymphoma isolated to the right masticator and left psoas muscles. Eur Radiol 2000; 10(5): 841-3.
[http://dx.doi.org/10.1007/s003300051015] [PMID: 10823644]
[14]
Harnsberger HR, Bragg DG, Osborn AG, et al. Non-Hodgkin’s lymphoma of the head and neck: CT evaluation of nodal and extranodal sites. AJR Am J Roentgenol 1987; 149(4): 785-91.
[http://dx.doi.org/10.2214/ajr.149.4.785] [PMID: 3498332]
[15]
Beggs I. Primary muscle lymphoma. Clin Radiol 1997; 52(3): 203-12.
[http://dx.doi.org/10.1016/S0009-9260(97)80274-7] [PMID: 9091255]
[16]
Zhang L, Lin Q, Zhang L, Dong L, Li Y. Primary skeletal muscle diffuse large B cell lymphoma: A case report and review of the literature. Oncol Lett 2015; 10(4): 2156-60.
[http://dx.doi.org/10.3892/ol.2015.3505] [PMID: 26622811]
[17]
Katsura M, Nishina H, Shigemori Y, Nakanishi T. Extranodal lymphoma originating in the gluteal muscle with adjacent bone involvement and mimicking a soft tissue sarcoma. Int J Surg Case Rep 2015; 7: 161-4.
[http://dx.doi.org/10.1016/j.ijscr.2015.01.024] [PMID: 25618843]
[18]
Hosono M, Kobayashi H, Kotoura Y, Tsuboyama T, Tsutsui K, Konishi J. Involvement of muscle by malignant lymphoma: MR and CT appearances. J Comput Assist Tomogr 1995; 19(3): 455-9.
[http://dx.doi.org/10.1097/00004728-199505000-00021] [PMID: 7790558]
[19]
Negendank WG, al-Katib AM, Karanes C, Smith MR. Lymphomas: MR imaging contrast characteristics with clinical-pathologic correlations. Radiology 1990; 177(1): 209-16.
[http://dx.doi.org/10.1148/radiology.177.1.2399318] [PMID: 2399318]
[20]
Metzler JP, Fleckenstein JL, Vuitch F, Frenkel EP. Skeletal muscle lymphoma: MRI evaluation. Magn Reson Imaging 1992; 10(3): 491-4.
[http://dx.doi.org/10.1016/0730-725X(92)90522-2] [PMID: 1406100]
[21]
Ferrari C, Maggialetti N, Masi T, et al. Early evaluation of immunotherapy response in lymphoma patients by 18F-FDG PET/CT: A literature overview. J Pers Med 2021; 11(3): 217.
[http://dx.doi.org/10.3390/jpm11030217] [PMID: 33803667]
[22]
Alamdari A, Naderi N, Peiman S, Shahi F. Non-Hodgkin lymphoma with primary involvement of skeletal muscle. Int J Hematol Oncol Stem Cell Res 2014; 8(3): 55-7.
[PMID: 25642309]

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