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Current Pharmaceutical Analysis

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ISSN (Print): 1573-4129
ISSN (Online): 1875-676X

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Mini-Review Article

A Review on PCR and POC-PCR - A Boon in the Diagnosis of COVID-19

Author(s): Singaravelan Sindhuja, Sivaperuman Amuthalakshmi* and Calambur Nagarajan Nalini

Volume 18, Issue 8, 2022

Published on: 29 August, 2022

Page: [745 - 764] Pages: 20

DOI: 10.2174/1573412918666220509032754

Price: $65

Abstract

Since the global spread of covid-19, PCR predominantly has taken the lead in the diagnosis. It amplifies a particular DNA target sequence into millions of copies. To simplify the laboratory- dependent disease diagnosis, the point of care diagnostics (POC) paved the way for labon- a-chip-technology. Succeeding that, POC integrated with PCR stole the limelight. This review points out the various diagnostic methods of covid-19 based on PCR and POC-PCR along with its principles, and types clustered regularly interspaced short palindromic repeats (CRISPR) based assays for the rapid, accurate, and easier detection of covid-19.

Keywords: PCR, Diagnostic techniques, covid-19, POC-PCR, DNA sequencing, CRISPR.

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