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Current Cardiology Reviews

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ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

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General Review Article

Current Treatment Options for the Failing Fontan Circulation

Author(s): Bart W. Driesen, Michiel Voskuil and Heynric B. Grotenhuis*

Volume 18, Issue 4, 2022

Published on: 17 March, 2022

Article ID: e060122200067 Pages: 15

DOI: 10.2174/1573403X18666220106114518

Price: $65

Abstract

The Fontan operation was introduced in 1968. For congenital malformations, where biventricular repair is unsuitable, the Fontan procedure has provided a long-term palliation strategy with improved outcomes compared to the initially developed procedures. Despite these improvements, several complications merely due to a failing Fontan circulation, including myocardial dysfunction, arrhythmias, increased pulmonary vascular resistance, protein-losing enteropathy, hepatic dysfunction, plastic bronchitis, and thrombo-embolism, may occur, thereby limiting the life-expectancy in this patient cohort. This review provides an overview of the most common complications of Fontan circulation and the currently available treatment options.

Keywords: Pediatrics, heart defects, congenital, fontan, complications, treatment.

Graphical Abstract

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