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Mini-Review Article

囊外淋巴结扩展预测结直肠癌的结果：简短总数

卷 23, 期 4, 2022

发表于: 05 October, 2021

页: [358 - 363] 页: 6

弟呕挨: 10.2174/1389450122666211005114122

价格: $65

摘要

背景：转移性淋巴结通过包膜延伸到结周或结外的脂肪组织定义了结外延伸（ENE）。 ENE 是多种癌症的重要预后因素，被认为是不同肿瘤-淋巴结转移 (TNM) 分类中的预后参数。 简介：结直肠癌（CRC）在发病率上排在第三位，排在肺癌和乳腺癌之后。淋巴结转移已被证实是结直肠癌 (CRC) 生存的一个重要的负面预后因素，这种情况可通过佐剂得到改善。尽管在多种癌症中使用 ENE 作为重要且经过验证的预后因素，但 ENE 尚未在 CCR 分期系统中考虑。 方法：本简短回顾旨在根据新出现的证据讨论 ENE 对 CRC 的预后影响。为了进行这项研究，我们按照科学原理将所有可用研究的结果分为三个部分：回顾性研究、前瞻性研究和荟萃分析。 结果：ENE对结直肠癌的预后有负面影响，但尚未在结直肠癌的实践中使用。 结论：因此，我们建议开展随机临床试验以更好地研究该主题并加强其在管理策略中的价值。

关键词: 结直肠癌、淋巴结转移、结外扩散、预后、结直肠癌中的 ENE、化疗

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