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Research Article

微创手术或CPAP治疗的OSAHS患者生活质量的变化：一项为期2年的回顾性单中心平行研究

卷 20, 期 3, 2020

页: [231 - 239] 页: 9

弟呕挨: 10.2174/1566524019666191009150734

open access plus

摘要

背景：通过纳入未经治疗的阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者作为对照组，本研究探讨了微创外科手术治疗和持续气道正压通气（CPAP）治疗对OSAHS患者的影响，具有主观和客观表现。该研究还讨论了它们之间的关系，确定了影响因素，并提供了一种简单而实用的方法来评估临床疗效。 方法：选择2014年5月至2016年5月在四川省睡眠障碍诊治中心诊断为OSAHS的90例患者。这些患者分为三组：手术组，CPAP组和未治疗组。对这些患者分别进行了六个月，一年和两年的随访。比较这三组的生理指标，临床症状，白天嗜睡程度和生活质量。评价微创手术和CPAP治疗前后的白天嗜睡情况和生活质量，并探讨手术和CPAP治疗的主观和客观疗效。 结果：在这90名患者中，有11名（12.2％）患有高血压，而2名（2.2％）患有糖尿病。平均AHI评分为每小时50.53±23.39，平均最低氧饱和度和平均氧饱和度分别为71.25±14.16％和90.13±5.90％。在接受0.5年和一年手术的组中，口呼吸，早晨咽喉痛和白天嗜睡情况有统计学差异。在CPAP组中，在0.5年，一年和两年时，口呼吸，早晨咽喉痛和白天嗜睡情况存在统计学差异。此外，一年和两年时记忆丧失的统计学差异显着，而一年一度的频繁夜尿存在统计学差异。手术组的ESS值在0.5年和一年时降低，但在两年后升高。就总点数和SF-36参数的每个维度而言，情况都是相同的。三组之间的ESS差异值在0.5年，一年和两年时具有统计学意义，其中CPAP组变化最大，其次是手术组，并且该组接受了健康教育。 结论：对于微创手术，CPAP治疗和健康教育可以改善白天的嗜睡和生活质量。发现CPAP疗法是最有效的，其次是微创手术并提供健康教育。但是，OSAHS的治疗应全面。

关键词: OSAHS，微创手术，CPAP，生活质量，睡眠障碍，睡眠。

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