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Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020)

Journal: Current Medicinal Chemistry
Volume: 28 Issue: 19 Year: 2021 Page: 3825-3842
Author(s): Jingwei Wu,Huan Zhang,Guilong Zhao,Runling Wang

Small-molecule Modulators Targeting SHP2 for Cancer Therapy

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 23 Issue: 5 Year: 2023 Page: 498-504
Author(s):

Structure, Function, and Pathogenesis of SHP2 in Developmental Disorders and Tumorigenesis

Journal: Current Cancer Drug Targets
Volume: 14 Issue: 6 Year: 2014 Page: 567-588
Author(s): Wen-Qing Huang,Qing Lin,Xuan Zhuang,Liang-Liang Cai,Run-Sheng Ruan,Zhong-Xian Lu,Chi-Meng Tzeng

Design Potential Selective Inhibitors for Treating Cancer by Targeting the Src Homology 2 (SH2) Domain-Containing Phosphatase 2 (Shp2) with Core Hopping Approach

Journal: Protein & Peptide Letters
Volume: 21 Issue: 6 Year: 2014 Page: 556-563
Author(s): Yu-Qing Duan,Ying Ma,Xue-Jiao Wang,Yuan-Yuan Jin,Run-Ling Wang,Wei-Li Dong,Wei-Ren Xu,De-Xin Kong,Shu-Qing Wang

Synergistic Cytotoxicity Effect of 5-Fluorouracil and SHP2 Inhibitor Demethylincisterol A3 on Cervical Cancer Cell

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 22 Issue: 7 Year: 2022 Page: 1313-1319
Author(s): Yang Liu,Hua Fu,Li Zuo

SHP2 Inhibition Benefits Epidermal Growth Factor Receptor-mutated Non-Small Cell Lung Cancer Therapy

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 21 Issue: 11 Year: 2021 Page: 1314-1321
Author(s): Leiming Xia,Lu Wen,Siying Wang

Aqueous Extract of Arbutus unedo Inhibits STAT1 Activation in Human Breast Cancer Cell Line MDA-MB-231 and Human Fibroblasts Through SHP2 Activation

Journal: Medicinal Chemistry
Volume: 4 Issue: 3 Year: 2008 Page: 219-228
Author(s): S. Mariotto, A. R. Ciampa, A. Carcereri de Prati, E. Darra, S. Vincenzi, M. Sega, E. Cavalieri, K. Shoji, H. Suzuki

Recent Developments, Challenges and Opportunities in Targeting theKRAS Pathway

Journal: Letters in Drug Design & Discovery
Volume: 20 Issue: 8 Year: 2023 Page: 992-1004
Author(s): Manoj Kumar Pothuganti

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 12 Issue: 5 Year: 2013 Page: 665-679
Author(s):

A Leap into the Chemical Space of Protein-Protein Interaction Inhibitors

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 30 Year: 2012 Page: 4648-4667
Author(s): B. O. Villoutreix,C. M. Labbe,D. Lagorce,G. Laconde,O. Sperandio