Nandrolone Decanoate Enhances the Activities of Cholanthrene Induced Glutathione-s-Transferase in Liver Tissue of Albino Mice

Title: Nandrolone Decanoate Enhances the Activities of Cholanthrene Induced Glutathione-s-Transferase in Liver Tissue of Albino Mice

Volume: 4 Issue: 1

Author(s): Biswajit Kumar Acharjee, Rita Mahanta and Aparajita Borkotoky

Affiliation:

Keywords: Xenobiotics metabolism, glutathione-s-transferase, anabolic steroid, nandrolone decanoate, 3-methylcho-lanthrene, liver

Abstract: A concrete study is still fragmentary to correlate the effect of Nandrolone decanoate, a anabolic steroid, on the cholanthrene induced Glutathione-s-transferases (GST) activities in liver tissues. Administration of Nandrolone and 3- Methylcholanthrene in alone and combination is found to increase the activity of hepatic GST activity significantly (p < 0.01) suggesting Nandrolone as a potent inducer of GST activity.

Cite this article as:

Acharjee Kumar Biswajit, Mahanta Rita and Borkotoky Aparajita, Nandrolone Decanoate Enhances the Activities of Cholanthrene Induced Glutathione-s-Transferase in Liver Tissue of Albino Mice, Drug Metabolism Letters 2010; 4 (1) . https://dx.doi.org/10.2174/187231210790980417