Xanthan Sulfuric Acid: An Efficient Bio-Supported and Recyclable Solid Acid Catalyst for the Synthesis of 2-minothiazole-5-carboxylates and 2-aminoselenazole-5-carboxylates

Title: Xanthan Sulfuric Acid: An Efficient Bio-Supported and Recyclable Solid Acid Catalyst for the Synthesis of 2-minothiazole-5-carboxylates and 2-aminoselenazole-5-carboxylates

Volume: 8 Issue: 8

Author(s): Bowroju S. Kuarm, Janganati V. Madhav and Bhargavi Rajitha

Affiliation:

Keywords: Bio-supported, N-bromo succinamide(NBS), recyclable, selenazoles, thiazoles, Xanthan sulfuric acid, inflammation, hypertension, bacterial, HIV infections

Abstract: An efficient method has been developed for the synthesis of 2-amino thiazole and selenazole-5-carboxylates from β-ketoesters, thiourea or seleno urea and N-bromo succinamide by using Xanthan sulfuric acid as a solid acid catalyst. The reaction work-up is very simple and the catalyst can be easily separated from the reaction mixture and reused several times in subsequent reactions.

Cite this article as:

S. Kuarm Bowroju, V. Madhav Janganati and Rajitha Bhargavi, Xanthan Sulfuric Acid: An Efficient Bio-Supported and Recyclable Solid Acid Catalyst for the Synthesis of 2-minothiazole-5-carboxylates and 2-aminoselenazole-5-carboxylates, Letters in Organic Chemistry 2011; 8 (8) . https://dx.doi.org/10.2174/157017811797249443