Relationship Among Adherence to the Mediterranean Diet and Anthropometric and Metabolic Parameters in Subjects with Obesity

Title:Relationship Among Adherence to the Mediterranean Diet and Anthropometric and Metabolic Parameters in Subjects with Obesity

Volume: 21 Issue: 9

Author(s): Luisa Lampignano, Roberta Zupo, Rossella Donghia, Vito Guerra, Fabio Castellana, Isanna Murro, Carmen Di Noia, Rodolfo Sardone, Gianluigi Giannelli, Vincenzo Triggiani and Giovanni De Pergola*

Affiliation:

• Population Health Unit - “Salus in Apulia Study” National Institute of Gastroenterology “Saverio de Bellis”, Research Hospital, Castellana Grotte, Bari,Italy

Keywords: Mediterranean diet, body fat distribution, cardiovascular risk, HDL cholesterol, waist to height ratio.

Abstract:

Background: There is moderate-to-high evidence that the Mediterranean diet prevents increases in body weight and waist circumference in non-obese individuals, but less is known about its effects in overweight and obese subjects. The present study was focused on exploring the cross-sectional association among the adherence to a Mediterranean diet and the most commonly used variables of metabolic and cardiovascular risk factors in a cohort of overweight subjects from a typical Mediterranean region, Apulia, in Southern Italy.

Methods: The study was performed in a cohort of 1214 individuals, all overweight or obese but with no other clinical condition. We investigated the association with adherence to a Mediterranean diet, assessed using the PREDIMED score, and anthropometric parameters [namely body mass index (BMI), WC, waist to height ratio (WHtR) and neck circumference (NC)], fasting serum levels of glucose, insulin, uric acid and lipids (triglycerides, total cholesterol, HDL cholesterol, and LDL cholesterol), and blood pressure and insulin resistance, measured by HOMA-IR.

Results: The waist to height ratio was negatively associated with a PREDIMED score ≥7 (p<0.04), whereas HDL cholesterol was positively associated with a PREDIMED score ≥7 (p<0.04).

Conclusion: This study suggests that body fat distribution and HDL-cholesterol are the parameters most strongly influenced by MedDiet in Apulian subjects.

Cite this article as:

Lampignano Luisa , Zupo Roberta , Donghia Rossella , Guerra Vito , Castellana Fabio , Murro Isanna , Di Noia Carmen, Sardone Rodolfo , Giannelli Gianluigi , Triggiani Vincenzo and De Pergola Giovanni *, Relationship Among Adherence to the Mediterranean Diet and Anthropometric and Metabolic Parameters in Subjects with Obesity, Endocrine, Metabolic & Immune Disorders - Drug Targets 2021; 21 (9) . https://dx.doi.org/10.2174/1871530320999201111161220