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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Caffeic Acid, A Versatile Pharmacophore: An Overview

Author(s): M. Touaibia, J. Jean-Francois and J. Doiron

Volume 11, Issue 8, 2011

Page: [695 - 713] Pages: 19

DOI: 10.2174/138955711796268750

Price: $65

Abstract

The caffeic acid scaffold, which is abundant in nature, is extremely versatile and is found in a number of biologically active molecules. The purpose of this review is to provide an overview of the pharmacological activity of synthetic caffeic acid analogs including recent reports of anti-inflammatory, anti-cancer, and antiviral activities of these compounds.

Keywords: Caffeic acid, anticancer, antioxidant, anti-inflammatory, integrase inhibitors, structure-activity relationships, Pharmacophore, scaffold, natural products, antiviral, synthetic caffeic acid


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