Abstract
Benzoxathiolones and its derivatives are important pharmacophores with diversified pharmacological activities like antibacterial, antimycotic, antioxidant and anti-inflammatory. These different biological applications for benzoxathiolone compounds have motivated new studies in searching novel derivatives with better activity results and also other applications in pharmaceutical industry. Owing to the importance of this system, the aim of this review is to present the main aspects of the chemistry and biological properties of 1,3- benzoxathiol-2-ones.
Keywords: 1,3-benzoxathiol-2-ones, synthetic methods, biological activity, 2,6-dihydroxythiophenol, 5,7-dibromo-6-hydroxy-benzoxathiolone, iminobenzoxathiol, Thioaurones, Iminobenzoxathiolones, LYR-71, crystallographic assay, epimerization
Mini-Reviews in Organic Chemistry
Title: Chemistry and Biological Activities of 1,3-Benzoxathiol-2-ones
Volume: 8 Issue: 1
Author(s): Walcimar T. Vellasco, Claudia R.B. Gomes and Thatyana R.A. Vasconcelos
Affiliation:
Keywords: 1,3-benzoxathiol-2-ones, synthetic methods, biological activity, 2,6-dihydroxythiophenol, 5,7-dibromo-6-hydroxy-benzoxathiolone, iminobenzoxathiol, Thioaurones, Iminobenzoxathiolones, LYR-71, crystallographic assay, epimerization
Abstract: Benzoxathiolones and its derivatives are important pharmacophores with diversified pharmacological activities like antibacterial, antimycotic, antioxidant and anti-inflammatory. These different biological applications for benzoxathiolone compounds have motivated new studies in searching novel derivatives with better activity results and also other applications in pharmaceutical industry. Owing to the importance of this system, the aim of this review is to present the main aspects of the chemistry and biological properties of 1,3- benzoxathiol-2-ones.
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Cite this article as:
T. Vellasco Walcimar, R.B. Gomes Claudia and R.A. Vasconcelos Thatyana, Chemistry and Biological Activities of 1,3-Benzoxathiol-2-ones, Mini-Reviews in Organic Chemistry 2011; 8 (1) . https://dx.doi.org/10.2174/157019311793979882
DOI https://dx.doi.org/10.2174/157019311793979882 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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