Abstract
Solid- phase synthesis is an approach, where synthetic transformation in carbohydrates are carried out with one of the reactant molecule attached to an insoluble material referred as polymeric support via linker. In recent years, it has been extensively accepted as fast and accurate method for the synthesis of biologically active oligosaccharides. This review attempts to focus on various methods of oligosaccharide synthesis by solid- phase including their applications.
Keywords: Carbohydrate, oligosaccharide, biologically active, solid- phase synthesis, linkers, protecting groups, glycosylating agents
Mini-Reviews in Medicinal Chemistry
Title: Solid-Phase Synthesis of Oligosaccharide Drugs: A Review
Volume: 9 Issue: 2
Author(s): Meenakshi Dhanawat and Sushant Kumar Shrivastava
Affiliation:
Keywords: Carbohydrate, oligosaccharide, biologically active, solid- phase synthesis, linkers, protecting groups, glycosylating agents
Abstract: Solid- phase synthesis is an approach, where synthetic transformation in carbohydrates are carried out with one of the reactant molecule attached to an insoluble material referred as polymeric support via linker. In recent years, it has been extensively accepted as fast and accurate method for the synthesis of biologically active oligosaccharides. This review attempts to focus on various methods of oligosaccharide synthesis by solid- phase including their applications.
Export Options
About this article
Cite this article as:
Dhanawat Meenakshi and Shrivastava Kumar Sushant, Solid-Phase Synthesis of Oligosaccharide Drugs: A Review, Mini-Reviews in Medicinal Chemistry 2009; 9 (2) . https://dx.doi.org/10.2174/138955709787316083
DOI https://dx.doi.org/10.2174/138955709787316083 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Cucurbitacin B Induces DNA Damage, G2/M Phase Arrest, and Apoptosis Mediated by Reactive Oxygen Species (ROS) in Leukemia K562 Cells
Anti-Cancer Agents in Medicinal Chemistry Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment
Mini-Reviews in Medicinal Chemistry Ovarian Toxicity: From Environmental Exposure to Chemotherapy
Current Pharmaceutical Design Molecular Imaging with Nucleic Acid Aptamers
Current Medicinal Chemistry Cervical Cancer: Are There Potential New Targets? An Update on Preclinical and Clinical Results
Current Drug Targets Targeting Microtubules to Inhibit Angiogenesis and Disrupt Tumour Vasculature:Implications for Cancer Treatment
Current Cancer Drug Targets Development of Drug Targeting and Delivery in Cervical Cancer
Current Cancer Drug Targets Prevention and Treatment for Chemotherapy-Induced Peripheral Neuropathy: Therapies Based on CIPN Mechanisms
Current Neuropharmacology YB-1 Activities in Oncogenesis: Transcription and Translation
Current Cancer Therapy Reviews MicroRNAs and Lung Cancer: New Oncogenes and Tumor Suppressors, New Prognostic Factors and Potential Therapeutic Targets
Current Medicinal Chemistry Idronoxil as an Anticancer Agent: Activity and Mechanisms
Current Cancer Drug Targets Vascular Endothelial Growth Factor: A New Paradigm for Targeting Various Diseases
Current Angiogenesis (Discontinued) Impact of Magnetic Nanoparticles in Biomedical Applications
Recent Patents on Drug Delivery & Formulation Antisense Treatment in Human Prostate Cancer and Melanoma
Current Cancer Drug Targets The Long and Winding Road to Cancer Treatment: The Trail System
Current Pharmaceutical Design The Problem of Amino Acid Complementarity and Antisense Peptides
Current Protein & Peptide Science Oxidative Stress in the Cochlea: An Update
Current Medicinal Chemistry Development of Arene Ruthenium Antitumor Complexes
Mini-Reviews in Medicinal Chemistry Resveratrol and Clinical Trials: The Crossroad from In Vitro Studies to Human Evidence
Current Pharmaceutical Design Toll-Like Receptors: Cost or Benefit for Cancer?
Current Pharmaceutical Design