Abstract
There is an increasing evidence that Helicobacter pylori may interfere with gastrointestinal metabolism of micronutrients and drugs such as iron, cobalamin, thyroxine and levodopa, with relevant clinical effects. In this review we examine the strength of the causal association and the plausible pathophysiologic mechanisms underlying these adverse effects.
Keywords: Helicobacter pylori, iron, cobalamin, thyroxine, levodopa, malabsorption, gastritis, gastric acidity
Mini-Reviews in Medicinal Chemistry
Title: Helicobacter pylori Interference with Micronutrients and Orally AdministeredDrugs:ANewMechanism Explaining its Role in Extragastric Disorders
Volume: 8 Issue: 2
Author(s): A. Pietroiusti, A. Galante, A. Magrini and A. Bergamaschi
Affiliation:
Keywords: Helicobacter pylori, iron, cobalamin, thyroxine, levodopa, malabsorption, gastritis, gastric acidity
Abstract: There is an increasing evidence that Helicobacter pylori may interfere with gastrointestinal metabolism of micronutrients and drugs such as iron, cobalamin, thyroxine and levodopa, with relevant clinical effects. In this review we examine the strength of the causal association and the plausible pathophysiologic mechanisms underlying these adverse effects.
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Pietroiusti A., Galante A., Magrini A. and Bergamaschi A., Helicobacter pylori Interference with Micronutrients and Orally AdministeredDrugs:ANewMechanism Explaining its Role in Extragastric Disorders, Mini-Reviews in Medicinal Chemistry 2008; 8 (2) . https://dx.doi.org/10.2174/138955708783498177
DOI https://dx.doi.org/10.2174/138955708783498177 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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