Inhibition of Aromatase (AR) by Benzyl Azole-Based Compounds

Title: Inhibition of Aromatase (AR) by Benzyl Azole-Based Compounds

Volume: 4 Issue: 8

Author(s): Shaheen Adat, Caroline P. Owen and Sabbir Ahmed

Affiliation:

Keywords: Enzyme, Inhibition, Azole, Estrogen synthetase, Aromatase

Abstract: We report the results of the evaluation of a series of benzyl imidazole-based compounds against the enzyme aromatase (AR). The results show that the synthesised compounds were potent inhibitors of AR in comparison to the standard compound aminoglutethimide (AG).

Cite this article as:

Adat Shaheen, Owen P. Caroline and Ahmed Sabbir, Inhibition of Aromatase (AR) by Benzyl Azole-Based Compounds, Letters in Drug Design & Discovery 2007; 4 (8) . https://dx.doi.org/10.2174/157018007782794554

DOI https://dx.doi.org/10.2174/157018007782794554	Print ISSN 1570-1808
Publisher Name Bentham Science Publisher	Online ISSN 1875-628X