Regional Anesthesia and Analgesia: Their Role in Postoperative Outcome

Title: Regional Anesthesia and Analgesia: Their Role in Postoperative Outcome

Volume: 1 Issue: 3

Author(s): G. Ekatodramis

Affiliation:

Keywords: EPIDURAL ANESTHESIA

Abstract: Increasing insight into the mechanisms of perioperative physiologic responses and the resultant effects on patient outcome suggests that some responses may be detrimental to long-term recovery. Thus, initial belief in the adaptive wisdom of the body [1] has been supplanted by the concept that a stress-free perioperative period may minimize detrimental physiologic responses and resultant morbidity [2]. The perioperative use of neuraxial- or regional anesthesia and analgesia have profound inhibitory effects on the bodys response to surgery compared to the same operation performed during general anesthesia alone. Increasing evidence has emerged suggesting that such afferent nociceptive blockade may improve a variety of postoperative morbidity parameters and improve surgical outcome. We review the clinical evidence from studies examining the effects of regional anesthesia and analgesia on postoperative morbidity in specific physiologic systems.

Cite this article as:

Ekatodramis G., Regional Anesthesia and Analgesia: Their Role in Postoperative Outcome, Current Topics in Medicinal Chemistry 2001; 1 (3) . https://dx.doi.org/10.2174/1568026013395236