Neprilysin 2: A Novel Messenger Peptide-Inactivating Metalloprotease

Title: Neprilysin 2: A Novel Messenger Peptide-Inactivating Metalloprotease

Volume: 11 Issue: 5

Author(s): Tanja Ouimet

Affiliation:

Keywords: neprilysin, neprilysin 2, m13 family of metalloproteases, peptide inactivation, enkephalin, substance p, thiorphan, phosphoramidon

Abstract: Neprilysin 2 is a recently identified glycoprotein displaying the highest degree of sequence identity with neprilysin (EC 3.4.24.11), the prototypical member of the M13 family of zinc-dependent metalloproteases. Whereas neprilysin has been shown to be involved in the inactivation of endogenous messenger peptides, like enkephalins and tachykinins, the true physiological functions of neprilysin 2 remain unknown.

Cite this article as:

Ouimet Tanja, Neprilysin 2: A Novel Messenger Peptide-Inactivating Metalloprotease, Protein & Peptide Letters 2004; 11 (5) . https://dx.doi.org/10.2174/0929866043406625

DOI https://dx.doi.org/10.2174/0929866043406625	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305