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Current Nutrition & Food Science

Editor-in-Chief

ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

Celiac Disease: An Emerging Epidemic

Author(s): Peter H.R. Green and Anne R. Lee

Volume 1, Issue 3, 2005

Page: [245 - 251] Pages: 7

DOI: 10.2174/157340105774574811

Price: $65

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Abstract

Celiac disease is a genetically determined autoimmune disorder induced by an environmental agent, gluten. The disease involves the development of a T-cell mediated inflammatory reaction to ingested gluten in the small intestine that results in villous atrophy. The manifestations of the disease are varied. Patients may be critically ill due to a severe malabsorption syndrome or asymptomatic. The reason for the varied phenotypic expression of the disease is unclear. The mainstay of therapy is a gluten-free diet that may be a testing endeavor in this culture.

Keywords: gluten sensitive enteropathy, HLA-DQ2, IgA endomysial antibody, gluten-free diet, autoimmune diseases, Selective IgA deficiency


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