Carbohydrate Antigens: Synthesis Aspects and Immunological Applications in Cancer

Title: Carbohydrate Antigens: Synthesis Aspects and Immunological Applications in Cancer

Volume: 6 Issue: 12

Author(s): Teresa Freire, Sylvie Bay, Sophie Vichier-Guerre, Richard Lo-Man and Claude Leclerc

Affiliation:

Keywords: Glycosylation, cancer, glycosyltransferase, synthesis, vaccine, immunotherapy, carbohydrate

Abstract: Tumor Associated Carbohydrate Antigens (TACAs) constitute powerful tools as tumor markers and as targets for anticancer immunotherapy. In this review, methods of production of glycopeptide-based vaccines, as well as results of preclinical and clinical studies in cancer patients are discussed.

Cite this article as:

Freire Teresa, Bay Sylvie, Vichier-Guerre Sophie, Lo-Man Richard and Leclerc Claude, Carbohydrate Antigens: Synthesis Aspects and Immunological Applications in Cancer, Mini-Reviews in Medicinal Chemistry 2006; 6 (12) . https://dx.doi.org/10.2174/138955706778992996